Rather than Survival, surely it should be either Seeds of Doom (end of series 13) or Logopolis (17 years later)?

Anyway, definitely yes. The main changes from Rose to Flux are improved effects and the story being slightly more serialised. With the classic series, as well as changes in production, the character of the Doctor and the ethos of the show had changed. What was the story of two teachers trying to return home had become the adventures of a heroic alien and his friends.